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Still, aside from several heavily studied genera, one of which (Biomphalaria) has direct importance for human health, the entire realm of gastropod genomics remains to be developed.
This is of direct importance for the development of vaccines, which may need to be designed more specifically for individual countries.
Since degeneration of motor terminals and peripheral motor axons precedes motor neuron cell death [6] [8], adverse interactions between TSCs and motor terminals or between axons and myelinating cells could be of direct importance for determining loss of motor unit function in B6.SOD1 mice and conceivably trigger more widespread motor neuron degeneration.
The demonstration that daily anti-HSV-2 therapy can reduce the viral load by this amount is thus of direct importance for treatment.
When validated, the modified-PUQE was significantly associated with an outcome of direct importance for women who experience NVP such as QOL (SF-12 PCS: p < 0.0001; SF-12 MCS: p = 0.0008).
The characterization of SLC gene expression in growing oocytes and during ovarian maturation has direct importance for understanding oogenesis in teleosts (Reading et al. 2012), especially in the context of egg buoyancy in pelagophilic marine species.
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The direct importance of immunity to mushroom tyrosinase for the melanoma disease is obtained from the study in which it is reported that mice immunized with mushroom tyrosinase generated a high titer of anti-tyrosinase antibodies which after the inoculation of melanoma cells developed a lower number of lung metastases compared with an unvaccinated control group [ 23].
Although some of these may be valid surrogates for future disease (for example, blood pressure, HDL and LDL cholesterol, and waist circumference) and some are of direct importance to patients (for example, weight loss), the value of other outcomes is unclear (for example, fasting blood insulin).
Studying how evaluations are processed based on different kinds of information is of direct practical importance for understanding choice behavior in a range of real-life scenarios (e.g., medical decision making, financial trading).
(2) T I i m = ∑ q ∈ m φ q, i m = ∑ q ∈ m ∑ i ≠ j r m, j i m In this study we measured topological importance for direct interactions (TI) and for proteins that lie 4-steps away from the target (TI).
The side chains of Phe-481 and Phe-483 are involved in interacting with an aromatic ring of a substrate although the importance for direct substrate recognition by these sites is ambiguous (de Groot et al. 1999; Rowland et al. 2006).
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