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μMAPPS retrieves pixel-by-pixel the collagen fibrils anisotropy and orientation by operating directly on two coupled phasor spaces, avoiding direct fitting of the polarization dependent SHG signal.
The estimation of the standard rate constant can be carried out either by direct fitting between the simulated and experimentally measured data, or by using the working curves derived by simulations.
Simulation and experimental results show that in ideal condition without any noise in the system, direct fitting yields perfect results without error; the algorithms including Southwell reconstruction achieve better results under practical conditions, where there exist real issues such as noise and abnormal data.
Intermediate tallies away from the extremes tend to be sparsely sampled even for quite large data sets, however, which can complicate direct fitting.
For direct fitting of selected polymorphisms to PK parameters, SNPs were converted to dichotomous categorical variables whereby the heterozygous category (M/m) for the major (M) and minor (m) alleles was combined with either the major or minor allele category as previously reported [33], [34].
Kinetic analyses were either carried out by direct fitting to simple first order equations or by numerical integration of sequential reactions.
Similar(51)
Pharmacological data should directly be fit to specific models and parameters derived from that direct fit.
To overcome this problem, a direct fit algorithm is suggested to calculate the coefficients of the frequency components.
Now offers a similar device for the leg or arm, said to be more convenient and to provide a more direct fit over muscles.
We obtained the electrostatic charges of HT-T and HT-AT, calculated at their equilibrium MP2/6-311G+ geometry, by a direct fit of the molecular electrostatic potential.
The RMS norm parameter therefore represents the goodness-of-fit of the estimated input function to the blood-sampled data relative to the goodness-of-fit of a direct fit of Equation 4 to the blood-sampled data.
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