Sentence examples for direct disruption from inspiring English sources
"For anybody that wants to follow in our footsteps, this is a direct disruption of freedom of speech, this is like a muzzle," Fara said, adding that they will keep fighting the ruling.
Directly ionizing radiation (e.g., a beam of protons, alpha particles, or beta particles) causes direct disruption of the atomic or molecular structure of the tissue through which it passes.
Recently, Lu et al. [26] have proposed that the influence of AuNPs on CYP2B1-mediated stereoselective metabolism may be due to a combined effect of direct disruption of enzyme conformation and indirect alteration in ionic strength of microenvironment for co-factor production.
This indicates that artemisinin and its related derivative OZ209 kill malaria by a similar mechanism all through direct disruption of mitochondrial functions.
A direct disruption or punctation of the vertebral artery, however, will not be avoided by IOUS.
Rituximab cytotoxicity is mediated by different mechanisms; ADCC, CDC, direct disruption of signalling pathways and the triggering of apoptosis.
And two important industries in the region, tourism and transportation, are suffering direct disruptions that will be hard to overcome.
There were no direct disruptions to the KEPC HV transmission network (generation sites, lines or transformer facilities) as the result of tephra fall, although over 24 km of circuits and transforming stations were exposed to more than 3 kg/m2 of tephra, and 10 km to over 10 kg/m2 (Fig. 2(d) and Table 5).
Therefore, we constructed a capsule-deficient strain of C. gattii, using a homolog of the C. neoformans CAP59 gene, for directed disruption, because this gene was originally identified as critical for capsule synthesis [14].
We conclude that the observed clinical severity of the cTnT Δ160E mutation is caused by a combination of direct sarcomeric disruption coupled to a profound dysregulation of Ca2 + homeostasis at the cellular level that results in a unique and highly progressive pattern of ventricular remodeling.
Our results demonstrate a clear role for CTCF in rDNA regulation, but formally we cannot show that this effect is direct, since disruption of CTCF or PARP/PARG are expected to have pleiotropic effects on other genes in the genome.
