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The data provide a direct demonstration of a template function for a telomerase RNA and demarcate the outer boundaries of the telomeric template.
These data provide the first direct demonstration of a specific regulation of an important RNA helicase gene by HIF-1.
Our study is a direct demonstration of a functional link between Tra1 and Tti2.
However, a direct demonstration of a causal link between immunosenescence and infections or tumors is still missing.
A more direct demonstration of a role in biotic defense comes from the fact that overexpression of AtPrx21 in Arabidopsis produces resistance to Botrytis cinerea[ 40].
These conclusions were further supported by work from Andrew McMahon's lab, including the recent direct demonstration of a gradient of Shh in the neural tube (Gritli-Linde et al, 2001; Jeong and McMahon, 2005; Chamberlain et al, 2008).
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It's the first direct demonstration of an excitement call in these animals, says Peter Madsen, a biologist at Aarhus University in Denmark who was not involved in the study. .
Although the direct demonstration of an association between Arc signals and cellular activity is still lacking, accumulating evidence suggests that neuronal activity of cells precedes the Arc expression (Lyford et al. 1995; Steward and Worley 2001; Shepherd et al. 2006).
Without any direct demonstration of an interaction of TPP1 and the TEN domain that is mediated by the charge swap mutants that are described, the conclusions here are not supported by the data.
However, among these four different experiments, the only direct demonstrations of an interaction between the accessory helix of complexin and the SNARE complex were the crystal structures, and the ITC experiment.
A direct demonstration of this is obtained from a comparison of the null space of the internal stoichiometry matrix in the full network and in the subnetworks.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com