Sentence examples for direct and essential role from inspiring English sources

"You can find no revolution in the world like the Islamic Revolution where the nation played a direct and essential role in its victory and advancement," he said, according to the official Islamic Republic News Agency.

Intriguingly, recent data has shown that the proneural protein Mash1/Ascl1 plays a more direct and essential role in both progenitor maintenance and neuronal differentiation.

In fact, it is most likely that thermotolerance is conferred by a whole suite of genes, with Hsp101 playing a direct and essential role (Hong et al. 2003).

In summary, local or systemic stem cells seem to play a fundamental and essential role in the regeneration of meniscus injury, either as direct repair cells or as a source for secretion of bioactive modulators.

These are different and essential roles.

Surprisingly, we found that the role of PHA-1 in pharyngeal development appears to be restricted to a small subset of cells and that PHA-1 does not appear to have a direct or essential role in pharyngeal cell specification or differentiation.

The future characterization of these complexes and their role in the HIV-1 life cycle can identify proteins that are direct and essential targets of viral proteins.

The system has been studied extensively and there is a direct evidence for its essential role in virulence in Y. pestis and other pathogens [10], [11].

Our results indicate substantial differences between various (anti folate substrates in their binding to hRFCs with mutated Ser, and in inducing conformational changes involving the proximal end of TMD8 by protein cross-linking, in direct support of a essential role for this region and Ser in binding and/or membrane translocation of (anti folate substrates.

In another case, the gene Peg10 is critical for mouse parthenogenetic development and provides the first direct evidence of an essential role of an evolutionarily conserved retrotransposon-derived gene in mammalian development [ 35].

DOI: http://dx.doi.org/10.7554/eLife.08421.015 In summary, the combination of single molecule measurements and MD computations has enabled direct identification of the essential role of intra-protein forces in driving the PFO complex into its final pore conformation.