Sentence examples for direct alteration from inspiring English sources

This cytokine produces an immediate decrease in contractile function that is not due to altered calcium transits, indicating direct alteration in contractile proteins [ 102].

Oxidative stress has been associated with the disruption of tight junctions by several mechanisms such as the elevation of oxidized membrane lipids that alter the localization of tight junction proteins and the direct alteration of claudins extracellular redox sensitive motifs [ 37– 39, 64].

Overall, the researchers found that about 14percentt of the losses were caused by direct alteration of the landscape by activities such as logging and land-clearing.

A heterologous gene expression system allows strain improvement to produce new metabolites by direct alteration of the biosynthetic pathway.

We have divided these strategies into three broad categories: (1) recruitment of catabolic genes, (2) expression of "repair" or detoxification proteins, and (3) direct alteration of enzymatic properties.

In Dr de Martini's experiment, soon to be published in Physical Review Letters, Kirk is not actually a separate photon, but a direct alteration to A. The net effect, however, is the same.

Epigenetics refers to changes that alter gene transcription in the absence of direct alterations to the genome itself [ 8].

Multiple mechanisms may contribute to sepsis-associated organ dysfunction, which is related to altered tissue perfusion, especially in the early stages, and to direct alterations in cellular metabolism.

Today, we have reached the position where direct alterations of the human genome at the DNA level are technically feasible although still clumsy.

We specifically hypothesize that the heterogeneity of vegetation structure plays an important role in the EBC due to its direct alterations of the outgoing (or reflectance) of short- and long-wave radiation that determine the magnitude of net radiation.

Secondly, we did not assess the course of changes in NRS and HRV across time; as such, the temporal relationship to direct alterations in NRS and HRV were not shown, because we focused on whether HRV could be a clinical surrogate predictive of postoperative pain in surgical patients who were pain free upon arrival in PACU.