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Aid workers say their conditions are dire, with many suffering malnutrition.
The public finances are dire, with current spending twice as high as revenue.
"We were warned the budget would be dire with a capital D".
The situation in New York is dire, with both the city and the state rolling toward a budget cliff.
Our country faces serious fiscal and other challenges, and they are about to become even more dire with the year-end "fiscal cliff".
When Murrells, a former Sainsbury's and Tesco executive, joined in the summer of 2012, trading was dire, with like-for-like sales down 5%.
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Pancreatic ductal adenocarcinoma has a dire prognosis with 85% of patients presenting with tumors that are unresectable.
Dire comparisons with Pakistan and Colombia are commonplace.
The world is in dire straits with water.
She also defends the child-abandoners — "mothers in dire circumstances, with no alternatives".
The beef situation had grown dire, along with the weather report.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com