A shift in research focus for glioma is also justified with dire statistics: glioblastoma multiforme (GBM) is the most common, and unfortunately, also the most highly malignant glioma.
The problems are obvious and the consequences dire, but with the UK's production and distribution system so firmly established making changes will require more than a shift in consumer demand.
While some European producers fear that digitization will hasten a shift in audience tastes, away from the kinds of films that Europe does best, the situation may not be as dire as the market share numbers suggest.
As public approval in the U.S. has shifted in favor of marriage rights for gay and lesbian couples, some in the LGBT rights movement have turned their attention abroad, where the situation is often more dire.
They are living in dire circumstances, caught in the crossfire.
But Claren also knows firsthand that if trans Mormons don't speak up, and if the church doesn't shift its views on LGBT members, the consequences will continue to be dire – and in some cases deadly.
The dire conditions in Xochimilco have generated debate among biologists.
CSD tends to correlate with more dire outcomes in cases of hemorrhagic stroke.
