Sentence examples for dire importance from inspiring English sources

For years, education advocates have highlighted the dire importance of closing the achievement gap of academic performance between students of different ethnic and socioeconomic groups.

This is especially important to note if you are faking sick or staying home for a reason that is not of dire importance.

Based on analyses using tissue specificity gene expression datasets, the developers of DiRE show that an importance score cutoff of 0.10 is reasonable for achieving good specificity and precision [ 45], therefore we used this cutoff to identify those tfbs that are significantly enriched in sequence surrounding up or downregulated genes from each dataset (Additional File 4).

"Symbolically, her reintroduction into the political life of the country at such a dire moment is of enormous importance".

The fine margins that assume even greater importance for clubs in dire straits are looming large for Ramsey before Saturday'sgame at Liverpool.

However, the protection of financial consumers is an issue that has not had the expected development just having a particular importance because of the dire consequences of financial crises.

To paraphrase Japan's Prime Minister Naoto Kan, in this dire time of need, we must appreciate the importance of the bonds that tie us together as part of a global community with common humanity.

Based on MW test results [see Additional file 12: The results of Mann-Whitney tests (CONFAC)], on the Importance score [see Additional file 10: DiRE motif discovery results for BDNF and 84 conserved correlated genes] and on the conservation data (UCSC), we propose potential regulators of BDNF [see also Additional file 13: Highly conserved TFBSs in the BDNF gene (according to DiRE and CONFAC)].

Despite these clear challenges, the dire need for novel therapeutic paradigms highlights the importance of seeking out commonalities in HGT mechanisms and exploring the plausibility of targeting these pathways.

The dire state of northern bluefin tuna populations underscores the importance of assessing the luxury trade in tuna.

NA - not applicable for the TFBSs discovered using DiRE [see Additional files 10 and 11 for TFBS importance score].