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"dire complications" is correct and usable in written English.
It can be used in situations where there are serious or severe problems or issues. Here is an example: "The patient's condition worsened overnight, leading to dire complications that the doctors were struggling to control."
Exact(6)
Tardiness is not tolerated, but the wrong body size can lead to dire complications; like dancers, supers tend to be on the thin side, which is not lost on Mr. Brody, a sprightly gentleman with a fluffy white beard.
(I'm still unclear on why Cupid, ostensibly Roman, is taking orders from the Greeks, but until I figure it out, I'm sticking with the idea that there were dire complications in the passport office.) At any rate, Cupid appears to be stymied in his efforts to forge romantic affiliations.
Families who transferred assets during the go-go years may now be stuck with relatively larger gift and estate tax bills or other, more dire complications.
Because we lament the prevalence of obesity and its often dire complications, especially in children, but blithely continue- as you have likely heard me say before- to market multicolored marshmallows as part of a complete breakfast.
Failure to diagnose and treat SAH can lead to dire complications including aneurysm rebleeding, cerebral infarction, and ultimately death [ 6].
In an attempt to attenuate the dire complications of hypertension, clinicians are faced with an array of antihypertensive agents.
Similar(54)
PFEMP1 protrudes from the knob to engage with various endothelial receptors, such as ICAM-1, CD36 and CSA, causing the cytoadherence of the IE to the endothelial cells and its sequestration in the microvasculature - the dire clinical complications of this disease, such as cerebral malaria and placental malaria, are the consequence of this phenomenon [7].
As Mr. Blount drifts from the river's northern headwaters at Lake Itasca, Minn., to its gaping mouth at the Gulf of Mexico, he learns that life on the Mississippi retains primeval charms in some places (a man in Illinois harvests catfish by hand) and fosters dire 21st-century complications in others.
Tuberculosis is already at epidemic levels, and an expected surge in AIDS cases and hepatitis complications could, by the most dire models, kill more than half a million people a year in a generation or two.
A frequently neglected complication of the disease with dire social and economic consequences is the loss of sight due to diabetic retinopathy, caused by damage to the blood vessels in the retina.
If they do survive, the consequences on the next generation are still dire: low birth weight, poor cognitive development, maternal health complications, etc.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com