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The laser was optically pumped by a high-power laser diode that was coupled into the cavity through a mirror coated for high transmission at the diode wavelength (808 nm) and high reflectance at the lasing wavelength (1064, nm).
These values are averaged together at each laser diode wavelength.
The percent deviation of the optical properties from their mean values at each laser diode wavelength is then calculated.
Dichroic beam splitter is selected to have a suitable spectral response (cut-off wavelength at 500nm, 85/15 at laser diode wavelength of 653nm) to be used for both fluorescence and DHM.
A multi-channel laser Doppler perfusion monitor (semiconductor laser diode, wavelength 780 nm, output power 1 2.5 mW, cut-off frequency 15 Hz, Oxford Array, Oxford Optronix, Oxford, UK) was used to measure red blood cell flux (RBC flux).
Near-infrared light consisting of a laser diode (wavelength, 780 nm) is used because it is more comfortable for the subject and provides retinal image quality estimates that are comparable to those obtained with visible light.
Similar(53)
Both phantoms have "similar" optical properties at the six laser diode wavelengths which require the calibration.
Choice of near-infrared laser diode wavelengths for LSCI is restricted by the two photon excitation center wavelength, which ultimately governs the transmission cutoff of D3.
We then fit the SS reflectance intensity at each of the laser diode wavelengths to the reflectance calculated from the FDPM-measured absolute absorption values.
The laser diode wavelengths are slightly different (several nm) for each DOSI system; hence we averaged the optical property values at similar wavelengths because the phantom optical properties are not sharply-varying at these wavelengths.
Three diode wavelengths will be used: the first two will be chosen based on work in submission on wavelength optimization [ 30] to discriminate for oxy- and deoxy- hemoglobin and a third will be added to assess for methemoglobin to allow the imaging of chronic rather than acute hematomas.
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