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With diminishing mortality and better overall quality of care, it will be increasingly difficult to study paediatric septic shock, owing to sample size, selection bias and ethical issues.
With diminishing mortality and a long list of influencing variables, more than 2,000 children per group are easily needed to draw any strong conclusions [ 2, 7, 17].
Additionally, low-tidal-volume ventilation has become the standard of care in critically ill patients because of studies showing that its use improves outcome, including diminishing mortality, in patients with acute lung injury and also is likely to prevent the development of lung injury when used as the initial mode of ventilation [ 11- 14].
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I read about developmental economics and randomized control trials (RCTs), and how some interventions are over 100 times more effective than others at accomplishing the things we want like education, opportunities for all, diminished mortality and reduction of suffering.
Early monitoring of the cardiac output to improve peripheral perfusion can diminish mortality and complications in elderly patients.
Yet, the extract improved the clinical status and weight of guinea pigs and diminished mortality after cisplatin exposure [ 33].
Injection of CoQ10 into the rostral ventrolateral medulla (medullary origin of sympathetic vasomotor tone) of rats diminished mortality and lipopolysaccharide-induced hypotension during exposure to lipopolysaccharide [ 7].
Initial improvements in longevity primarily reflected diminished mortality from infections and were largely attributable to improvements in sanitation and nutrition and to the development of effective vaccines.
Thus, they provide a long-lasting target to evaluate the effects of immunoneutralization. Accordingly, we recently reported that ProCT markedly contributes to mortality in experimental sepsis, and that immunoneutralization of this molecule diminishes mortality in our model of hamster sepsis [ 36].
During remission: 1) exclusion of precipitating factors (education of patients and family doctors), 2) information about on-line drug lists, and 3) mutation screening for family members and education about precipitating factors in mutation-positive family members which can diminish mortality and prevent subsequent attacks among them.
Underlying this large effect was the fact that improved access to care greatly reduced baseline rotavirus mortality, diminishing the potential mortality benefit of vaccination.
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CEO of Professional Science Editing for Scientists @ prosciediting.com