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One might speculate that the presence of the myosin Va tail fragment either led to an augmented biosynthesis or to a diminished turnover of the synapse marker.
We also constructed mutant S119A, which putatively disrupts a critical hydrogen bond, as a negative control with which we expected diminished turnover of the epoxide product.
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This results in anoikis, a type of apoptosis characterized by cell detachment, and, consequently, a markedly diminished epidermal turnover time in psoriasis.
And since elevated pressure causes increased proliferation and down-regulates endocytosis, both proliferation and decreased endocytosis might cause synergistically diminished CSF turnover in affected areas.
We found that expression of a mutant cadherin-11 lacking the cytoplasmic juxtamembrane domain (JMD) diminished the turnover of α-catenin at adherens junctions as measured by fluorescence recovery after photobleaching.
Concerning i-FABP, the lack of diagnostic efficiency could be attributed to an insufficient amount of enterocytes undergoing perioperative necrosis, although the postoperative time-profile could also be considered partly at fault since the significant decreased levels of plasmatic i-FABP were probably caused by a diminished enterocyte turnover during the selected time period for the analysis.
Pressure on the quarterback diminished and turnovers were down.
Mr. Turner of the F.S.A. argues that diminishing the turnover of the financial sector would be a worthwhile objective in itself to reduce the amount of "socially useless activity".
It diminishes the turnover rate among physicians [ 16].
Similarly, organizational support improves work satisfaction and diminishes the turnover rate among physicians [ 67].
It could involve shifting the balance from fusion to fission, increasing mtDNA replication, stimulating the mitochondrial biogenic transcriptional cascade, diminishing mitochondria turnover or any combination of these regulatory pathways depending on the stage of neuronal differentiation.
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