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The emergence of drug-resistant strains has rapidly diminished the efficacy of current antibiotics, urging the development of more effective treatments and the identification of new therapeutic targets (2, 3).
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Not testing the partners might well diminish the efficacy of this simple field medicine approach.
Conflicting data exist as to whether proton pump inhibitors (PPIs) diminish the efficacy of clopidogrel.
Emerging trends – including cloud computing, user mobility and Bring Your Own Device (BYOD) – have further complicated matters, increasing the attack surface while diminishing the efficacy of traditional perimeter defences.
4B and 4D indicate that under higher susceptibility the addition of anger diminishes the efficacy of suppression but does not render it counterproductive.
However, patients receiving conventional platinum drugs often develop resistance, which diminishes the efficacy of the drugs.
Generation of neutralizing antibody may alter PK and subsequently diminish the efficacy of IL-13-PE.
The rising tide of multi-drug-resistant organisms (MDROs) is increasingly diminishing the efficacy of our antibiotic arsenal.
Emergence of BCR-ABL-independent pathways supporting proliferation or resistance to apoptosis will inevitably diminish the efficacy of imatinib monotherapy.
Previously, we showed that the Src inhibitor AZD0530 induces autophagy in prostate cancer cells, which contributes to apoptosis resistance and diminishes the efficacy of the Src inhibitor.
This finding implies the potential for applying LDR to protect normal tissues from radiotherapy without diminishing the efficacy of tumor therapy.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com