Sentence examples for diminished the activation from inspiring English sources

The doses of WTM and VN assayed diminished the activation induced by ETO of DNA-PKcs by a 49.6% and 58.4%, respectively; with no significant effect on ATM (data not shown).

Simultaneous knockdown of MAF1 with Pol III or BRF1 (subunit of TFIIIB) diminished the activation and looping effect, which indicates that recruiting Pol III was required for activation of Pol II-mediated transcription and chromatin looping.

We show here that in the case of PMT-mediated Gβγ activation the PI3 kinase inhibitor wortmannin diminished the activation of JNK, suggesting that there is a possible link between MAP kinase activation and PI3 kinase/Akt.

As shown in Figures 7(a) and 7(b), RTE markedly diminished the activation of MgSO4-induced PKA (all P < 0.05) and p-CREB (all P < 0.05), which are associated with the production of AQPs 2 and 3 in HT-29 cells.

Finally, interaction of APC with protease-activated receptor-1 can diminish the activation of macrophages and other cell populations [ 5- 7].

Here, we show that LBP pre-treatment could diminish the activation of GFAP and AQP4, as well as retinal swelling in retinal I/R injury, implying the inhibitory effects of LBP in retinal swelling by minimizing the activation of Muller cell and AQP4.

In several other tissues, basic fibroblast growth factor (FGF-2) has been shown to diminish the activation of myofibroblasts.

The level of the mutually exclusive cap-bound proteins (eIF4G and 4E-BP1) indicathatthat ectopically expressed 4E-BP1A37/A46 strongly diminishes the activation of the cap-dependent complex.

According to that model, diminishing the activation of the renine-angiotensin system and sympathical activation is thought to be essential in the treatment of patients with HF.

8 9 Naltrexone occupies µ-opioid receptors, which putatively diminishes the activation of mesolimbic dopamine and therefore may reduce craving for nicotine.

Nobiletin did however diminish the activation of later signalling modulators such as AKT and PLCγ2, both associated with PI3K signalling to regulate platelet function, particularly calcium mobilization.