Sentence examples for diminished side effects from inspiring English sources

Significant to this study, compounds 2 12 exemplify novel analogues of known pyrrolopyrimidine and pyrazolopyrimidine template-based Src kinase inhibitors that incorporate bone-targeting group modifications designed to provide tissue (bone) selectivity and diminished side effects.

The working hypothesis that underlies the computational study reported here is that ligands that bind with significant affinity to all three cloned opioid receptors, δ, μ, and κ, but with different combinations of activation and inhibition properties at these receptors, could be promising behaviorally selective analgesics with diminished side effects.

Therefore, a great effort has been made to develop analogs of vitamin D with similar antipsoriatic but diminished side effects.

This is an important result because it shows that BLM delivery can be significantly improved and its cytotoxic effect can possibly be attenuated by attaching it to a suitable vector, conceivably resulting in diminished side effects of BLM therapy.

Some studies have suggested that for cancer treatment, drug cocktails combining botanical and chemical medicines may exhibit enhanced efficacies with diminished side effects and complications [ 11- 13].

The results of our study provide further support for the involvement of IGF-1 or analogous compounds in the preservation and restoration of salivary glands following radiation which can lead to diminished side effects and provide head and neck cancer patients with the possibility for improved quality of life.

The design of novel drugs for pain relief with improved analgesic properties and diminished side effect induction profile still remains a challenging pursuit.

These compounds can be valuable candidates for novel behaviorally selective analgesics with diminished or no side effects, and thus with potential therapeutic usefulness.

This provides an excellent framework to aid in the design of novel antipsychotics with diminished propensity to produce clinically limiting side effects.

Scopolamine, a muscarinic acetylcholine receptor antagonist impairs multiple memory systems, and this has promoted the notion that drug-induced side effects are responsible for diminished task execution rather than selective impairments on learning and memory per se.

Such side effects could be profound, like a diminished ozone layer.