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In summary, we confirmed that KS cases have diminished DTH responses in the leg, and we also found evidence, albeit weaker, for diminished responses in the arm-plus-leg of elderly KSHV-seropositives who have not developed KS.
Summing unit responses over a small patch of cortex in macaque V1 would produce a strong response to stimuli at one visual location in the contralateral field and greatly diminished responses to all other visual locations.
Patient 510013 had strong responses to autologous viral peptide and moderately diminished responses to I437L and (K436R, I437V) variants.
The latter demonstrates that the diminished responses to IP3 were not due to thimerosal activating IP3R3 and thereby draining the Ca2+ stores before addition of IP3.
A recent study by Schroeder et al. found low basal plasma cortisol levels and diminished responses to corticotropin-releasing hormone in patients that died of septic shock as compared with those who survived [ 17].
The suppressive activity of 4-1BB might dominate early, resulting in diminished responses to M45 and M57 responses, because 4-1BBL is not expressed at high levels during the very early phase of infection.
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In patients with sepsis, the Frank-Starling curve is shifted downwards and to the right, with septic patients showing a diminished response to fluid loading.
The catechol-imprinted electrode shows the usual diffusion-limited cyclic voltammogram of catechol and has a diminished response against all catecholamines.
Noticeable reduction in macular edema and central macular thickness was consistently observed 14 to 30 days following the injection with diminished response observed in the visits following day 120.
A diminished response to unexpected high wins suggests that integration of reward signals is deficient in the drug condition.
Our results, however, extend these findings and indicate that repeated exposure to violent media leads to diminished response in this region and functional disconnection from the amygdala, as well as increased response in motor planning areas.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com