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While there may be many reasons for the worse stroke outcome in women, it is interesting that the onset and diminished outcome of stroke in women parallels the time period of falling E2 levels that occurs after menopause.
Higher proinflammatory cytokine levels appear to be responsible for diminished outcome in male victims of trauma [ 9].
The biology of the recurring tumour might dictate the outcome, but given the diminished outcome of patients left with positive margins, surgical efforts should aim to achieve microscopically clear margins during the resection of recurrent tumours.
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Other studies have associated patella infera after TKA with decreased post-operative range of motion, extensor lag, anterior knee pain, anterior polyethylene impingement and wear, and diminished outcomes [5, 6, 7, 8, 9].
Occurrence of patella infera or baja after total knee arthroplasty has been well reported in the literature, wherein patellofemoral mechanics may be altered, resulting in a decreased post-operative range of motion, extensor lag, anterior knee pain, anterior polyethylene impingement and wear, and diminished outcomes [5, 6, 7, 8, 9, 10].
Power et al. (2004) found a significant decrease (9.5 %) of MVC force that was associated to the reduced ITT (5.4 %) and therefore concluded that neurological effects could have caused that diminishing outcomes.
That's what we do.' " In the nineteen-sixties, federal policymakers were influenced by scientific research that established direct connections between childhood disadvantage and diminished educational outcomes.
The existing evidence suggests that, although older spinal cord injury (SCI) patients experience a similar degree of neurologic recovery to younger patients, older patients experience diminished functional outcomes at follow-up.
24 These observations also appear consistent with comparable findings of others outlined in Table 3, the significantly diminished functional outcomes these individuals may experience as outlined by Lübbeke and colleagues, 25 and the need to investigate and treat all potential determinants of this very disabling problem.
When targeting the brain, though, every cubic millimetre destroyed unnecessarily risks diminishing the outcome for the patient.
The premature drug release of the payload drug from nanocarriers diminishes the outcome of nanoformulations for targeted drug delivery, yielding only marginal improved therapeutic index and toxicity profile.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com