Sentence examples for diminished its activity from inspiring English sources

Attachment of the cellulase to the cell surface, either by anchoring it to the cell wall or by attaching it to the scaffoldin, diminished its activity.

Knockdown of BiP increased the efficacy of the drug and overexpression of BiP diminished its activity.

Mutating the aspartic acid to glutamic acid (D427E) generated a hyperactive form of Skn7p, whereas a mutation to asparagine (D427N) diminished its activity (Li et al. 1998).

Importantly, the M-cell-CM prepared in the presence of IWP-2 also completely diminished its activity to induce invasion and secondary EMT phenotype in both E-A549 and E-Panc cells (Fig. 4b,c).

Dopamine can covalently modify and inactivate parkin through its conjugation with cysteine (431) (Lazarou et al., 2013) at its reactive center or making it becoming insoluble that diminishes its activity.

These findings also suggest that the impact of LoNA on chromatin state is achieved by binding to NCL to diminish its activity, rather than its expression.

Binding of FKBP to BiP suppresses its ATPase activity, thereby diminishing its activity [ 26].

SIRT3 deacetylates cyclophilin D, diminishing its activity and inducing its dissociation from ANT.

Tau phosphorylation at both of these regions plus the microtubule-binding region nearly diminishes its activity and disrupts microtubules.

Our in vitro data support the hypothesis that this locus possesses enhancer activity and indicate that the risk alleles of rs10816625 and rs13294895 can diminish its activity, indicating that these are independent risk susceptibility variants acting through the same mechanism.

Furthermore, the electrostatic binding of SDS to quaternized chitosan diminished its antibacterial activity and (because the SDS-bearing mixtures with strong biocidal activity were limited to low surfactant concentrations) also resulted in limited hydrophobe solubilization.