Exact(7)
In this proof of concept study, we observed a modest but consistently diminished incidence of nephrotic range proteinuria in spironolactone-treated mice.
Unlike established platinum and taxane-based regimens, trabectedin/PLD was associated with greatly diminished incidence of neuropathy and alopecia, as well as lack of end organ, cumulative toxic effects.
We found diminished incidence and severity of EAE disease in Stat5−/− mice compared with Stat5+/+ mice, which was opposite to our expectation based on an inhibitory role of STAT5 in TH17 generation.
Radiological cerebral atrophy however appeared less frequently here than previously reported (≤13% here vs. ≥30% [4], [31]), probably because of the diminished incidence of HIV-associated dementia and because cryptococcosis is more often revelatory of AIDS than in the pre-HAART era [41].
Novel NO donors offering selective effects, a prolonged half-life, and a diminished incidence of drug tolerance have been developed to overcome these limitations.
However, at ten and 12 weeks substantial MIN development is noted in wild type mice, compared to a greatly diminished incidence of MINs in NG2 null mice.
Similar(52)
Conversely, targeting both patient-to-patient transmission and sporadic sources would dramatically diminish incidence.
Our results support radiography as an effective screening tool for IDC and also by implication as a tool to diminish incidence of IDD in Dachshunds.
This leaves us to conclude that these ancient strains were indeed highly similar to modern strains and, therefore, the diminishing incidence of leprosy in Europe was not caused by the evolution of M. leprae to a distinct genotypes that was less virulent or less transmissible.
In particular, these include whether or not herders announce themselves to local bodies, establishment of social ties that might diminish incidences of aggression, acceptance of local rules on tree cutting, and reduction of livestock theft.
Treatment with NAC in drinking water in pregestational diabetic mice completely eliminated the incidence of AVSD, TGA, TOF and significantly diminished the incidence of ASD and VSD.
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