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In contrast, the IV administration of virus resulted in a markedly diminished OVA specific CD8+ T cell response in the liver as detected by tetramer staining (Fig. 1A) with a likewise markedly diminished frequency of CD8+ T cells responding to specific peptide stimulation in vitro with IFN-γ production (Fig. 1B).
Although IL-17 and IFN-γ expression by CNS-infiltrating Stat5−/− CD4+ T cells was not impaired, we detected a significantly diminished frequency of CD4+GM-CSF+ cells in the CNS of Stat5−/− mice compared with control mice.
Treatment of NZB/W mice with anti-IFN-γ or deletion of the IFN-γ receptor resulted in prolonged survival, diminished frequency and delayed onset of proteinuria, decreased autoAb levels, and decreased histopathologic evidence of glomerulonephritis [ 37- 39].
It has been postulated that active TB infection is immunosuppressive and that treatment of TB would lead to improved immune function and an increase in antigen-specific IFN-γ production by T cells.[ 17] Our data support an alternate hypothesis that treatment leads to decreased antigen burden and, in turn, diminished frequency of circulating antigen-specific T cells.
And if the owner cares little about the cost savings of fewer fill-ups, surely the diminished frequency of those stops won't go unappreciated.
The main reasons for this limited knowledge include (1) the diminished frequency of catheter-related treatment failures due to advancements in manufacturing and (2) the limited application of the treatment in different clinics.
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He explained in the dictionary's foreword that the sexual and excretory vulgarities were "so well known as to require no explanation," while what he called the "true obscenities," the ethnic slurs, are "encountered with diminishing frequency these days".
In Batho's case, the diminishing frequency and volume of new postings since his website started three years ago suggest that – in his case, at least – the urge to preserve Taylor Parkes's live reviews for posterity may be growing fainter.
Inter-cell interference is a major bottleneck in the performance of current and future cellular systems, which are gradually pushing toward diminishing frequency reuse factors and dense deployments.
The speed of sound in a typical liquid is 1000 1500 m s−1, and the ultrasonic wavelengths will vary from roughly 10 cm down to 100 µm over a diminishing frequency range of 20 15 MHz, which is much larger than the molecular-size scale.
Wetlands ranged from being permanently inundated, connected multiple times per year due to both small fluctuations in river level and the annual flood pulse, to flooded with diminishing frequency depending on the size of the annual flood pulse and their position on the floodplain.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com