Sentence examples for diminished expression of the from inspiring English sources

Objective: We tested the hypothesis that apoptotic trophoblasts from pregnancies associated with fetal growth restriction caused by preeclampsia or cigarette use exhibit enhanced expression of the proapoptotic proteins p53 and Bax and diminished expression of the antiapoptotic protein Bcl-2.

Therefore, one may speculate that diminished expression of the glycoprotein in the hippocampus leads to altered output in the corresponding cortical projection areas.

Instead, these cells underwent apoptosis that correlated with diminished expression of the pro-survival gene Bcl2A1.

Furthermore, diminished expression of the putative S100 protein receptor RAGE did not affect the observed phosphorylation of IκBα.

Several laboratories have also demonstrated loss or diminished expression of the RARβ2 mRNA in primary breast cancers [ 11, 12].

The gene expression profiles showed a diminished expression of the main angiogenic and lymphangiogenic factors in breast cancer.

It has been proposed that the combined diminished expression of these genes, rather than the inactivation of one single classical TSG, could cause the unfavorable outcome associated with 1p deletions in neuroblastoma.

The diminished expression of these transcripts would suggest a decrease in the synthesis of both glucosinolates and methionine within the leaves of the nhx1 plants.

This led us to postulate that cubilin might undergo an allelic inactivation that silenced or strongly diminished expression of either the maternal or paternal allele.

The diminished expression of MDM2 from the Mdm2puro allele is dependent upon insertion of the Puro gene into the non-coding intron 6 of the Mdm2 gene [38].

Some sporadic human cancers also show abnormalities in MMR gene function, typically due to diminished expression of one of the MutL homologs, MLH1.