As shown for GR, at saturating concentrations of hormone the inhibitory effect was greatly diminished, even though TPR2, for example, still reduced GR's activity twofold (Fig. 3B).
When these cells were simultaneously treated with a c-ABL kinase inhibitor, STI571, or a c-ABL-specific siRNA along with adriamycin, the p53-dependent p21 induction was dramatically diminished, even though p53 is substantially induced.
In the last six or seven years, however, seizures have diminished even though European cocaine consumption has remained unchanged, Mr. Pietschmann said.
The need for residential care does not appear to have diminished even though a number of initiatives including Ageing-in-Place have been implemented [ 5].
Like many veterans, but for different reasons, he came home to find his glory days diminished, even though he was still young.
The administration had benefited from the impression that it had diminished Al Qaeda, even though the public no doubt appreciates that it was never going to be so simple.
Individuals heterozygous for a single centric fusion may present diminished reproductive capacity, even though the trivalent structures formed segregate normally during meiosis [ 17].
Even though the sport diminished in popularity, boxing remained a constant in Las Vegas, through the high times and the recession that hit in 2008.
This was independent of age group, even though the risk diminished over the study period.
However, even though the risk diminishes over time, it is still higher than the rate among the destination country-born population even 10-20 years later [ 46- 48].
