Sentence examples similar to diminished efficacy level from inspiring English sources

To investigate whether the diminished efficacy of ART in young poor responders compared to young normal responders is due to a quantitative or a qualitative oocyte factor.

She decided on her own to increase her daily dose to 15 milligrams, from the 10 milligrams prescribed by her doctor, to counteract what she perceived as diminished efficacy of the drug over time.

The chronic administration of 0.625 mg/kg lorcaserin significantly reduced alcohol intake up to 6h every day after the injection and there was no sign of diminished efficacy of the drug during 10-day treatment.

Diminished efficacy of endogenous TxA2 and direct depolarisation secondary to dysfunction of the RhoA/ROK pathway may contribute to systemic hypotension in septic shock and dysregulation of regional blood flow [18,20].

Slightly diminished efficacy was observed for lhRNA rev-vif-tat e.

KD025 was also safe in a permanent ischemia model, albeit with diminished efficacy.

LSCs usually reside in a quiescent state, resulting in the diminished efficacy of chemotherapeutic agents targeting cycling cells.

Studies have consistently shown that lower adherence is associated with diminished efficacy and increased health care costs.

To determine whether vector clearance correlated with diminished efficacy against HBV replication, HD Ad genome copies were quantified in mouse livers.

This correlated with a prolonged HB22.7 half-life and validates our hypothesis that receptor saturation by HB22.7 results in a loss of target and diminished efficacy.

Over the past years, studies based on in vitro model systems revealed several mechanisms that may contribute to diminished efficacy with PIs and acquisition of resistance.