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Aging mouse SSCs (>1 year) exhibit functional deficiencies, showing reduced proliferation in vitro and diminished colonization ability in vivo [ 7].
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Recently, it was reported that treating plants with the ethylene precursor ACC, significantly diminishes colonization of Medicago sativa and Arabidopsis by Klebsiella pneumoniae or Salmonella [28].
Although it is conceivable that BAPN can target other cellular molecules in addition to LOX, our findings suggest that LOX inhibition was responsible for the diminished tissue colonization by the circulating MDA-MB-231 cells.
Our results showed that SRF overexpression increased the number of lung and intrahepatic tumor foci in a GC9811 xenograft model, whereas SRF reduction diminished the colonization of GC9811-P cells.
It has been shown that it can strongly diminish microbial colonization of the human skin [ 15].
Preexisting osteoarthritis of the right hip might have had diminished local defenses, thereby enabling colonization of the hip area by bacteria that had entered the bloodstream through the wound on the patient's hand.
Interestingly, AMF colonization in roots significantly diminished at 375 μg g−1 ZnONPs treatment compared to controls.
Immunization of two mouse strains with identified antigens provided protection from pneumococcal colonization that was significantly diminished in animals treated with blocking CD4 or IL-17A antibodies.
In such children the ingestion of inocula that might be sufficient to cause diarrheal illness in a child without environmental enteropathy may be diminished by innate defenses such that colonization occurs but clinical disease does not.
The TIGR4 pneumococcal pilus has been demonstrated to enhance initial adhesion, thereby conferring a specific colonization advantage (8), and diminished nasopharyngeal cocolonization by other niche competitors has been attributed to pneumococcal piliation (11).
The effects of susceptibility (2 alone) are diminished or negative because children protected against colonization have lower levels of immunity to (1) and (3) than unvaccinated children.
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CEO of Professional Science Editing for Scientists @ prosciediting.com