Exact(12)
Overall, this data fits with a recent study which demonstrated that children who were treated prophylactically with acetaminophen during vaccination had diminished antibody titers, although the majority had successful vaccine responses [13].
Importantly, reduction of T cell epitopes is not limited to avoiding immune recognition; it also results in reduced antibody titers and diminished antibody affinity.
Kapetanovic et al. studied the effect of ABT on the antibody response to PPSV23 in patients with RA (compared with TCZ) and reported marginally diminished antibody responses in the ABT group [ 8].
To explore whether the diminished antibody responses to H. pylori in prevalent TB patients might result from immune deficits associated with having active disease, we evaluated measles antibody responses in 100 Gambian culture-confirmed TB cases and 100 age- and sex-matched latently infected nonprogressors.
Current smoking was associated with diminished antibody response.
Among children with different rheumatic diseases only treatment with glucocorticoids was identified as a predictor of diminished antibody response [ 16].
Similar(48)
Thus blockade of IL-6 would be expected to diminish antibody production.
The propagation and growth of hybridoma cells under conditions of reduced serum diminishes antibody secretion by hybridoma cells [ 25- 27].
If results were calculated as positive, the test were repeated and confirmed by titrating down a 2-fold dilution series to 1 512 (data not shown) to ensure that fluorescence diminished with antibody dilution (as recommended in the product insert).
However, a number of problems that diminish antibody efficacy in a therapeutic setting still need to be addressed.
Thus amelioration of infection by 244 DI virus appeared to improve rather than diminish the antibody response to the A/Cal haemagglutinin.
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