Sentence examples for diminish expression of from inspiring English sources

Interestingly, other NK cell receptors may also play a role in MCMV immunity, as CMV encoded gp40 protein can diminish expression of protein ligands recognized by the NK cell receptor NKG2D.

Gold nanorod DARPP 32 siRNA complexes (nanoplexes) have been developed by group of scientists which can target and diminish expression of the key proteins (DARPP-32), extracellular signal-regulated kinase (ERK), and protein phosphatase 1 (PP-1) in the dopaminergic signaling pathway in the brain for ailment of drug addiction [84].

However, when we attempted to apply RNAi in the Latin American trypanosome, Trypanosoma cruzi, to diminish expression of mRNA encoding the surface protein amastin, we found that the amastin double-stranded RNA (dsRNA) was not efficiently degraded in either epimastigotes or amastigotes, and the level of amastin mRNA remained unchanged.

This technique has been employed to diminish expression of a variety cell surface molecules [ 44- 46].

For example, an experiment might be designed to see if siRNA can effectively diminish expression of IL-1, a key inflammatory cytokine involved in numerous diseases.

However, none of the rps5 Ssu− mutants exhibit diminished eIF1 abundance, or selectively diminish expression of the SUI1-lacZ fusion with native context.

Conclusion: In preeclampsia, increased endothelial cell monolayer permeability appears to reflect disorganized and diminished expression of endothelial cell junctional proteins.

Nature of effect(s) of each such specific factor, on mean (favourable or adverse) and on LoE (amplifying or diminishing expression of genotypic differences).

Both ribozymes diminished expression of CB mRNA, protein, and activity, without affecting cathepsin D or β-actin, as determined by quantitative real-time PCR, Western blots, and protease activity assays.

Generally, larger opinionated neighborhood sizes have an inhibitory effect on the expression of opinionated sentiments (Figure 2A-D): While both larger positive and larger negative neighborhood sizes have the expected inhibitory effect on the expression of the opposite sentiments (i.e., negative and positive, respectively), they also predict diminished expression of that same sentiment.

p21 is not only an inhibitor of cyclin-dependent kinases but it also diminishes expression of Beclin 1 and Atg5 [27].