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In a dimensional (quantitative continuum) condition, no single qualitative process can distinguish the extremes from normal variations.
Three Dimensional Quantitative Structure Activity relationship (3D-QSAR) studies, performed to optimize the lead, have been summarized at some places.
Comparative molecular field analysis (CoMFA) has been widely used as a standard three dimensional quantitative structure activity relationship (3D-QSAR) method.
The two dimensional quantitative structure-activity relationship (2D-QSAR) approach was used to investigate the catalytic activities for a date set of 58 2-azacyclyl-6-aryliminopyridylmetal complexes.
Three dimensional quantitative structure activity relationship (3D-QSAR) studies were carried out on deoxythymidine monophosphate (dTMP) derivatives inhibiting thymidine monophosphate kinase (TMPK) in Mycobacterium tuberculosis.
The identified 5 feature pharmacophore model, AHHPR, was validated via three dimensional quantitative structure activity relationship as indicated by r2, q2 and Pearson R values of 0.9013, 0.7726 and 0.9041 respectively.
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Using three-dimensional quantitative microscopy we show that sinusoidal endothelial and mesenchymal reticular subsets are remarkably more abundant than estimated by conventional flow cytometry.
ansa-Zirconocene complexes have been studied by Three-Dimensional Quantitative Structure Activity Relationship (3D-QSAR).
PKUDDS has been developed mainly for computer-aided drug design using the methods of two-dimensional quantitative structure activity relationships, three-dimensional quantitative structure activity relationships, molecular docking, and database screening.
The three-dimensional quantitative structure activity relationship (3D-QSAR) models were developed from the systematic search conformer-based alignment method.
Mass cytometry facilitates high-dimensional, quantitative analysis of the effects of bioactive molecules on human samples at single-cell resolution, but instruments process only one sample at a time.
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