Sentence examples for digestive barrier from inspiring English sources

Efficiently delivering hydrophilic and sensitive peptide drugs to safely transverse the digestive barrier with no effect on gut physiology using remains a key driver for formulation research.

Because of increased activity or the expanded spectrum of certain drug classes (e.g., β-lactam agents and fluoroquinolones) or of local therapy (e.g., extremely high concentrations in the gut after oral administration of glycopeptides that do not cross the digestive barrier) bacteria need to combine mechanisms that confer resistance to the same class of molecules.

Non-occlusive mesenteric ischemia is a common complication of shock regardless of the underlying etiology and is often considered as the main contributor to terminal multiple organ failure in relation with breaches in the digestive mucosal barrier [30].

Non-occlusive mesenteric ischemia is a common complication of shock regardless of the underlying etiology and is often considered as the main contributor to terminal multiple organ failure in relation with breaches in the digestive mucosal barrier [ 30].

For example, the digestive system barriers have to fight the bacteria from the gut that are constantly attempting to penetrate the body [1].

According to the International Conference on Harmonization (ICH) guidelines (www.ich.org) for pharmaceuticals, routine genotoxicity testing of protein is not considered necessary to confirm safety even when the protein drugs is administered parenterally, bypassing the digestive tract barriers discussed in previously in the section on current protein safety assessment considerations.

The gut in a homeostatic state equates with a functional digestive system, cellular barrier stability and properly regulated recognition of self and non-self antigens, as managed by a complex community of resident microbes.

Sample-level analysis at different time points in pregnancy demonstrated a strong correlation with cell types found in the intrauterine environment and fetal respiratory, digestive and external barrier tissues of the fetus, using high-confidence cellular molecular markers.

This association is probably the result of disseminated protothecosis in severely immunocompromised patients, and the alga may cross digestive or cutaneous barriers.

Firstly, this barrier prevents digestive enzymes with large molecular weights from being secreted into the exuvial cleft.

It is possible that the dietary fibre-rich bran fraction in brown rice can continue to serve as a barrier to digestive enzymes, but several other modes of action are also possible.