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MS/MS data of the tryptic digest provided varied sequence coverage of the three isoforms: PKN1 (53%), PKN2 (51%) and PKN3 (31%).
This procedure of reduction, alkylation and enzymatic digest provided also good sequence coverage of other Möbius cyclotides in mixtures namely varv A and vigno 5 (Supplementary Fig. S2; Supplementary Table S1).
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This digest provides an overview of the amidine containing class of BACE1 inhibitors, of which multiple examples are now progressing through clinical trials.
Thus, the expelled algae may also be digested, providing additional nutrients to the host without additional metabolic cost.
The Fidelity Select model portfolio of Timer Digest provides a good illustration of how the Sharpe Ratio can deflate what otherwise appears to be impressive performance.
Worse, many physicians rely solely on digests provided to them by pharmaceutical companies, which are even less likely to present drugs' effects objectively.
The MS/MS of the protein digests provided four peptide sequences (RPDEFAAR, FDALR, ITALNLR and TQTQLLALQR) that matched the B. pertussis hypothetical protein BP0500 (NCBI accession: NP_879352).
Using an affinity column with anti-SG antibodies to isolate adducts from proteolytic digests provides a concentrating step that greatly increases the sensitivity of detection.
In such cases, restriction digests provide an accurate, simple and cost-effective method to rapidly screen even large numbers of samples.
Since restriction digests provide a fast and cost-effective method to rapidly screen PCR products, we developed a restriction endonuclease digestion assay of the amplification products to confirm that they correspond to the E6 and E7 viral genes.
A6 The highly classified digest that provides President Bush with his daily intelligence updates is being scrutinized after criticism that information on Iraq and other matters has not reflected a broad range of views.
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