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This is a limitation to the diffusion of the technique as a quantitative imaging tool of regional lung function since, while purely manual delineation provides an accurate delineation [7], it is time-consuming and potentially operator-dependent.
Consequent diffusion of the technique led to extended series, reported in the mid '90s.
Before the widespread diffusion of the technique of mesorectal excision, many studies, including 4 randomized studies, had compared pre-operative radiotherapy (RT) versus surgery alone [ 6- 9].
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We believe that the diffusion of this technique will also contribute to the identification of new biomarkers and novel therapeutic strategies against cancer and other diseases.
With the diffusion of these techniques and new endoscopic tools, endoscopic procedures are becoming more and more complex and much longer lasting.
Throughout the grasslands there have been exchanges of art objects and diffusion of the brass-casting technique, confusing the more-detailed stylistic picture.
The requisite skills in complex statistical modeling will be a constraint to the wide-scale diffusion of the DALYs averted technique for monitoring impact.
According to Jean Gimpel, their high level of industrial technology facilitated the diffusion of new techniques: "Every monastery had a model factory, often as large as the church and only several feet away, and waterpower drove the machinery of the various industries located on its floor".
However, high computational requirements have limited the diffusion of such techniques for GNSS applications.
This 'bottom up' approach contrasts with models of diffusion of innovation that focus on the efforts of organizations to direct and secure the adoption and diffusion of new techniques and technologies deemed to add to effectiveness.
Traditionally, intracerebral drug injection techniques rely on diffusion of the therapeutic agent from the site of introduction, significantly limiting the volume of distribution [ 1].
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