In multiple sclerosis, the majority of active plaques show normal or increased diffusivity, but some may show restricted diffusion, often at the margins [68].
The presence of an ectopic, focal peripheral nodule characterised by low signal intensity on T2-WI, with sharply defined margins, restricted diffusion and enhancement similar to the central portion of the hypertrophied TZ, could be erroneously interpreted as PCa in the PZ [12, 13].
Using data relating to mail services we indicate the relative importance of the intensive and extensive margins in global diffusion over time.
An additional important use of DWI after surgical resection of a tumour is to detect areas of diffusion restriction in the cavity margins on MRI performed in the first 48 h, corresponding to small postsurgical infarctions.
Open image in new window Fig. 11 The arrows show a focal nodule bulging in the left peripheral zone, characterised by low signal intensity on axial (a) and coronal (c) T2-weighted imaging, with sharply defined margins, and restricted diffusion on the ADC map (b).
Previous ex situ TEM analyses of recovered samples revealed strong Fe depletion and Si enrichment in the hot area, and Fe migration to the cold margin through chemical diffusion due to a relatively large temperature gradient (Sinmyo et al. 2008; Andrault and Fiquet 2001).
This comparison indicates that the predicted chloride diffusion coefficient level is within a ±25% error margin in the specimens.
Regions of interest (ROI) on diffusion-weighted images were carefully identified in the margins or solid area and ADC values were recorded.
Neighboring the pluton margin, poly-sized (200 2500 μm) plagioclase grains in anorthosites are of two types: strain-free rectangular-shaped plagioclase grains with high-energy An-richer margins indenting neighboring plagioclase grains formed by diffusion creep, whereas unstrained end-to-end touching euhedral plagioclase grains showing tilling represent magmatic flow textures.
Similar to previous multi-generation single product diffusion models, we find that the planning horizon, the products' relative profit margin, and substitution effects are important to the launch time decision.
