This type of diffusion model is simple and tractable but may be oversimplified.
The diffusion method is simple, yet is routinely used in hospital laboratories; it requires commercial disks, the medium used is agar with 2% of glucose and the diameter of the zone of inhibition is visually read 18 h after incubation at 37 °C.
Although computation of a single solution of the advection diffusion equation (ADE) is simple, in general it is prohibitively expensive to compute the parametric variation of solutions over the full parameter space Q, even though this is crucial for, e.g. optimization, parameter estimation, and elucidating the global structure of transport.
While due to the lower diffusion of Cr in the UPN-inclusive lower rapid diffusional paths, the role of simple diffusion is higher.
Furthermore, simple diffusion is sufficient to capture the dynamics of other insect-pathogen interactions [77].
Our results also demonstrate that for the typical distances and time scales governing the cytoskeleton of a T15 cell, simple diffusion is actually quite sufficient to explain the rapid emergence of a strong FLAP signal at the leading edge.
We conclude that simple diffusion is sufficent to explain the observed transport rates, and that variations in the transport of labeled actin through the lamella are minor and not likely to be the cause of the observed physiological variations among different segments of the leading edge.
Simple diffusion is defined as having α = 1, and given the statistical variability in the data, we considered an α value <0.85 necessary to reliably indicate anomalous diffusion.
There are a number of basic modes for compounds to move across brain barrier membranes [ 5, 49, 50]: Simple diffusion is a passive process driven by the concentration gradient, from high to low concentrations.
Moreover, the impact of the deletion mutants on drug entry firmly establishes that transport via protein carriers, rather than simple diffusion, is likely to be the main route of cellular ingress for many drugs.
