Sentence examples for diffuse dissemination from inspiring English sources

Cellular invasion remains a significant cause of therapy failure as diffuse dissemination of tumor cells throughout the entire GBM brain including the normal appearing white matter precludes clean surgical margins.

Mizukami et al. found no effect of Treg counts on survival but showed that a diffuse dissemination of Treg was associated with poor survival while accumulation of Treg in the peritumoural region correlated with a more favourable outcome.

Melanoma metastases have been shown to have a high mutation rate [ 9], variable phenotype, a clinically diffuse dissemination pattern [ 10], and the unique ability to elicit spontaneous antigen-specific host immune responses [ 11].

Combined inactivation of p53 and E-cadherin leads to mILC, which is highly invasive and shows (lymph)angiogenic and diffuse dissemination with metastasis to the gastrointestinal tract and bone, similar to the human situation.

Imaging features are very similar to the classical astrocytomas, however they frequently present early with diffuse subarachnoidal dissemination.

Patients who presented with ascites and/or diffuse tumour dissemination in imaging modalities and without symptoms, which made an operative intervention inevitable, were not operated but received a systemic treatment.

Most patients with LMGC remain incurable due to bilobar, multinodular tumor spread, gross peritoneal dissemination, diffuse metastases to distant lymph nodes, or unresectable local recurrences [ 4, 15– 17].

Likewise, a grade 3 CXCR4 expression in our HCC patients was associated with a significantly reduced 3-year-survival, due to hepatic failure following diffuse intrahepatic HCC dissemination.

The patient was well tolerant to these therapies and without evidence of illness until July 2008, when CT scans demonstrated diffuse pulmonary metastatic dissemination (Fig. 3A) and a metastasis in right hepatic lobe.

Diffuse central neurocytoma with craniospinal dissemination.

In contrast, brain MRI, which is more sensitive that CT for detecting brain meningeal dissemination, showed a diffuse leptomeningeal enhancement, which was compatible with the diagnosis of MC.