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We hypothesized that the more diffuse development of fibrosis in RAGE KO mice would lead to a more impaired pulmonary function than the WT mice.
All these factors may explain why diabetics have accelerated progression and, often, more aggressive and diffuse development of coronary atherosclerosis in frequently smaller native vessels [ 3] and experience higher morbidity and mortality.
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The high school movement was spurred less by these diffuse developments than by legislation by Massachusetts in 1827 that ordered towns of 500 families to furnish public instruction in American history, algebra, geometry, and bookkeeping, in addition to the common primary subjects.
This principle may constrain the ability of China to address more complex and diffuse sustainable development challenges in the future.
Diffuse (fragmentary) development and subsequent piecemeal assembly of the pulmonary vascular system may explicate the fabrication of a complex circulatory architecture that grants cross-current, counter-current, and multicapillary serial arterialization designs in the exchange tissue of the avian lung.
Tatemichi et al. conducted a case-controlled study using gastric cancer cases and matched control subjects, and they demonstrated that high-titer patients have the highest risk for diffuse cancer development [ 80].
Sieverts is also known for his 1997 book Zwischenstadt - on the evolution of once-compact cities into diffuse webs of development clusters and all that means for society - and its 2003 English translation, Cities Without Cities (Rutledge).
In some of these studies, the relevant clinical characteristics of CWH have been described as being gradual in development, diffuse, throbbing, severe, intensified with exercise and distinct from migraine headache [9].
Here, we show that, during development, diffuse serotonin promotes spinal motor neuron generation from pMN progenitor cells, leaving interneuron numbers unchanged.
(3) Diffuse interstitial fibrosis: development of fibrosis suggested by chest X-ray or computed tomography or documented by open lung biopsy.
On one hand, we showed that both chicken scutate scale and alligator overlapping scale development have diffuse β-Catenin and Shh expression and form a diffuse LoGZ, which is different from the observed focal pattern of gene expression and LoGZ formation in chicken feathers (Fig. 1D R).
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