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This highlighted the difficulty to establish a regular nephrology care in very elderly.
This is mainly due to the difficulty to establish a quick collaboration with zebrafish lab working on SCRIB.
The difficulty to establish a link between phylogenetic groups on the one hand, and severity of infection in humans on the other hand, can have several causes.
As a result, the diagnosis of IVL is made postmortem in over 50% of the cases 3, 4. Furthermore, unlike primary CNS lymphoma with which a high responses rate is usually seen, the treatment of IVL remains suboptimal due to the rarity of this disorder and the difficulty to establish a diagnosis in a timely fashion.
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All of this results in difficulty to establish such a program and predict its trajectory at the early stages.
It is worth remarking that in the study of hyperbolic operators considered in this note, the major difficulties in order to establish a priori estimates regard to the case in which the function (beta x, lambda)= x_{0}+ lambda- alpha(x')) assumes positive and negative values in Ω̅.
The toxicity of SecTRAPs to A549 and HeLa cells could possibly explain prior difficulties encountered in attempts to establish a stable TrxR1-overexpressing cell line.
One difficulty is that "we need to establish a sophisticated approach to the body.
She was described as an introverted child, who had difficulties to establish social interactions.
In our experience we have observed the difficulties sometimes encountered when trying to establish a good quality relationship with some patients; there is the risk of inappropriate behaviour and unfortunate remarks that remain engraved in the patient's memory [ 1, 2].
Therefore, some difficulties to establish therapeutic guidelines persist.
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