Our laboratories experienced difficulty producing adequate quantities of recombinant human TFIIE-α for in vitro studies using available clones.
These problems were due to; "Lack of common terminology", "Subjective anxiety on evaluation of spatial quality and quantity", "Difficulties in expressing positive, negative and missing parts of student studies, through the design process assessments", "Problems of expression during information exchanges between project groups, etc".
The long hours, the quantity and difficulty of the work, and the pressure to excel are a recipe for frayed nerves, shortened tempers and durable frustrations.
Last week, the New York State Education Department took steps to ease some testing requirements after weeks of criticism from parents and teachers about the quantity and difficulty of the exams.
The resulting value, called inter-annotator agreement (IAA) or inter-coder agreement score is useful to assess how well the task is defined, how consistent the annotations are and it helps to quantity the difficulty of the annotation process.
Aspects of sleep raised by FM patients included poor sleep quality and insufficient quantity including difficulty with falling asleep, getting comfortable, and staying asleep; restlessness; light sleep; not feeling rested upon awakening; and difficulty starting the day.
We excluded pizza restaurant chains (such as Pizza Hut) because of the difficulty in determining the quantity that an individual bought for personal consumption, and we excluded restaurants that cater primarily to adults (such as Starbucks).
However, the interpretation of clinical examination is complicated, because of the difficulty in measuring the quantity and exact wavelength of light to which an individual has been exposed, as well as the length of time over which an injury has been progressing [ 54].
The Duchenne muscular dystrophy (DMD) mouse model, mdx, has previously been investigated with metabolomics using tissue extracts, but to our knowledge, serum has not been investigated using both H and C. One technical difficulty is the small quantity of sample available for NMR in mouse serum studies.
We excluded 717 participants from the analysis who had prevalent diabetes at the baseline survey conducted between 1999 and 2000, or those who did not report the quality or quantity of sleep (difficulty initiating sleep, difficulty maintaining sleep, and duration of sleep) at baseline.
The discovery of gold and silver in various regions and the difficulty of transporting large quantities of bullion through country menaced by Indians and bandits prompted the founding of both private and federal local mints.
