The difficulty for the human dignity version of this objection is to explain why the problematic feature of such research is best understood in terms of human dignity as opposed to moral status, autonomy, rights, and interests (Macklin 2003, DeGrazia 2007).
However, for many human diseases, and in particular in the case of meningococcal meningitis, the difficulty of reproducing the human disease in animal models has hampered the identification of novel virulence factors.
As for many human specific diseases, the difficulty of reproducing the human disease in animal models has hampered the identification of the neisserial attributes required for invasiveness.
Although the authors offered two related explanations for the effects of timbre on AP performance, neither addressed the issue of difficulties with the human voice.
It's a sentiment that could just as easily come from Inherent Vice, and it serves to remind the reader that for all of Pynchon's arcane references and postmodern gamesmanship, what he is at the end of the day is a writer of heartfelt sincerity who writes about the difficulty of being human in the modern world.
As a consequence of the obvious practical difficulties in investigations of the human TMJ, the sheep has been variously used as an animal model.
Finally, our study highlights the difficulty of collecting human resources data in the eye care sector.
Given the difficulty of procuring human brain tissue versus the relative ease of measuring blood expression levels, a question of great practical importance is to determine to what extent blood is a reasonable surrogate for brain in gene expression studies.
Jason's main concern has been to develop paths of healing the mind, body and spirit based on his own understanding of the difficulties inherent in the human condition.
However, discovering socially important locations from a social network is challenging due to the data size and variety, spatial and temporal dimensions of the datasets, the need for developing computationally efficient approaches, and the difficulty of modeling human behavior.
A third proposed solution has been to use nuclear transfer to create patient-specific lines, but this approach has proven technically difficult and it raises several significant practical and ethical issues, including the difficulty of obtaining human eggs in sufficiently large numbers and the concerns over producing cloned human embryos for use in research and therapy [ 24].
