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The shortcoming of this method is the difficulty of fixing the knife to the target lesion.
One important aspect of heterosis is the difficulty of fixing the favorable properties of the hybrids into a true breeding line, making repeated crosses from inbred lines the most practicable method of harnessing the benefits of heterosis.
This includes the observation that vigor increases as the parents diverge genetically up to a point where the parent populations become incompatible [ 46] and hybrids between them are at a severe disadvantage, as well as demonstrating the difficulty of fixing the hybrid trait in a true-breeding line [ 45].
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Three new books — Patrick Wright's "Passport to Peking" (Oxford; $34.95), Frank Dikötter's "Mao's Great Famine" (Walker & Co.; $30), and Timothy Cheek's anthology "A Critical Introduction to Mao" (Cambridge; $27.99) — attest to the difficulty of definitively fixing Mao's image, a project that amounts to writing a history of China's present.
In this paper, we look into how the increase of such executions have impacted a number of issues, including the occurrence of related bugs, the difficulty to fix these bugs compared to fixing non-concurrent ones, and the distribution of unreproducible concurrency and non-concurrency bugs.
Good chance of fixing.
Another complication impacting the scope of lustration arises from the difficulty in fixing degrees of guilt under totalitarian regimes.
The limitation of the regression procedure is that computational capacity runs into difficulties if the number of fixed effects is high.
fixed = number of fixed AFLP-fragments; Frag.
Because we adopt only two levels of reading passage difficulty, two fixed sources for retrieving reading passages were used: the Times in Plain English http://www.thetimesinplainenglish.com/ for low (easy) reading passages and the New York Times http://nytimes.com/ for high (difficult) reading passages4.
It's also the difficulty of finding them, and of understanding them well enough to fix them.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com