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One hurdle that has long faced teachers trying to incorporate macroevolution into their curricula is the difficulty of exploring the subject with hands-on, organism-centric labs.
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The harrowing difficulties of exploring the wreck unfold along with this mystery, with the group of divers tragically narrowing -- three are killed -- as the submarine stubbornly refuses to yield its secrets.
Given this difficulty of thoroughly exploring the chemical-space of drug like molecules, fragment-based approaches have emerged.
This is largely due to the difficulty of exploring an immense conformational space to identify the set of conformers that collectively best fits the experimental diffraction pattern.
The company's total production has barely budged since 2002, despite some major acquisitions, because of declines in older fields and the difficulty of exploring for new fields in a world where most oil is now controlled by national oil companies.
In the marine brown macroalgae, the morphological characters are highly similar between two widely distributed genera, Homoeostrichus and Zonaria (Dictyotaceae), thereby resulting in the difficulty of exploring their hidden biodiversity.
Royal Dutch Shell pulled out of its Arctic drilling campaign in 2015 after spending $7 billion because of the rising cost, significant public opposition and extreme difficulty of exploring in rough water rife with dangerous ice floes.
At first glance this appears surprising but could be explained by the technical difficulties of exploring a field where conditioned and conditioning stimuli overlap and vary in the same direction.
Previous work has shown that the continuous solver differential evolution (DE) can be successfully applied to this discrete problem, but has difficulty exploring the region of solutions with lowest resonant frequency.
Traditional hazard analysis techniques often rely upon static models of component interaction and have difficulties exploring the effects of multiple coincident failures.
Logical empiricists debated the merits of the two stances, exploring the difficulties of making precise the notion of partial interpretation and the possibility of finding axiomatic systems that would generate all the observational consequences without employing any theoretical vocabulary.
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