Sentence examples for difficulty of demonstrating the from inspiring English sources

However, this opportunity may be limited by several factors: the spontaneous interconversion of the two enantiomers, the pharmacokinetic profile or the selective toxicity of the most active enantiomer, and the difficulty of demonstrating the clinical superiority of one enantiomer over the racemate.

28 Given the absence of effect of the interventions on MSSA, the decline in MRSA prior to interventions, the strain specificity of the effect on MRSA and the difficulty of demonstrating the effect of an intervention package on MRSA isolation, 14 we find it difficult to estimate how much, if any, of the observed decline in MRSA isolations is attributable to recent infection-control measures.

Other limitations relate to the difficulties of demonstrating the 'impact' of patient involvement.

The excellent pro/con debate by George and Morris [ 48] in Critical Care clearly summarizes both the robust evidence to support the implementation of ASP and the difficulty of demonstrating a real impact in terms of reduction of length of stay or mortality.

Gillian Triggs, the president of the Australian Human Rights Commission, told the Senate a bar on proceedings would make it "virtually impossible" to bring forward any action, because of the difficulty of demonstrating bad faith in legal proceedings.

Ramus was aware of the difficulty of demonstrating his natural method in literature.

Furthermore, the results of the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) study (34) showed the difficulty of demonstrating beneficial effects of intensive glycemic control on CVD prognosis.

This illustrates the difficulty of demonstrating that a major cardiac event has been provoked by acute hypoglycemia in any individual diabetic patient, since simultaneous glucose and ECG monitoring is rarely possible in clinical practice.

The party, Li argues in a notably sycophantic essay, will overcome any short-term difficulties to demonstrate the superiority of China's wise, meritocratic, and public-spirited one-party system and expose the failings of western democracy.

However, our results and previous studies emphasise the difficulty in demonstrating the attributable impact of these procedures on clinical outcome.

6– 11 Difficulty demonstrating the success of iron supplementation programs in reducing anemia has led some to question their effectiveness.