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Gillian Triggs, the president of the Australian Human Rights Commission, told the Senate a bar on proceedings would make it "virtually impossible" to bring forward any action, because of the difficulty of demonstrating bad faith in legal proceedings.
Ramus was aware of the difficulty of demonstrating his natural method in literature.
However, this opportunity may be limited by several factors: the spontaneous interconversion of the two enantiomers, the pharmacokinetic profile or the selective toxicity of the most active enantiomer, and the difficulty of demonstrating the clinical superiority of one enantiomer over the racemate.
Health promotion specialists are often frustrated by difficulty of demonstrating effects of their educational efforts.
One main reason for this situation has been the long-standing difficulty of demonstrating intercisternal continuities in thin sections for electron microscopy.
Furthermore, the results of the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) study (34) showed the difficulty of demonstrating beneficial effects of intensive glycemic control on CVD prognosis.
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Other limitations relate to the difficulties of demonstrating the 'impact' of patient involvement.
It is clear that any such effects are relatively small compared to the efficacy of transfusions, which likely explains the difficulty of convincingly demonstrating them in small trials, where there are many confounding variables.
The conventional methods of confirming activity or relapse in an infectious disease have limited utility in leprosy because of the difficulty in demonstrating bacilli in paucibacillary (PB) cases and absence of a method of in vitro cultivation of Mycobacterium leprae.
A major problem regarding this hypothesis is the inability to link amyloid accumulation to the severity of the disease, and difficulty in demonstrating toxic forms of Aβ in AD brain.
He makes light of the formidable difficulties of Canteyodjaya, demonstrates that the Four Studies are much more than dry technical exercises and grades and minutely colours every strand of the aural landscapes that make up the Catalogue.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com