Exact(5)
Primary reasons not to prescribe a treatment were effectiveness for azathioprine, safety/tolerability for cyclosporine and cyclophosphamide, and a mixture of cost, safety/tolerability, and difficulty of administration for the biologic drugs.
In the case of adalimumab and infliximab, respondents cited a number of reasons not to prescribe these treatments, including cost, insufficient long-term data, concerns with safety and tolerability, and difficulty of administration.
Other prominent concerns for these biologic drugs included a lack of long-term data (24%and29%9%), safety/tolerability (22% and 20%), and difficulty of administration (38%and13%38%and13%
90 Concern of hypoglycemia and of difficulty of administration should not prevent an elderly patient from enjoying the benefits of improved glycemic control with insulin treatment, for example improved quality of life and vitality.
Other contributing factors may include improper dosage regimen during administration which includes difficulty of administration of drops of antibiotics in day time use for adult populations and children [ 38].
Similar(55)
Nevertheless, peptides present some limitations, related to their low capability to cross membrane barriers, short half-life, and difficulties of administration.
Some possible mechanisms by which the above predictors could affect treatment include difficulty of drug administration in those below three years of age, the high prevalence of underlying malnutrition which increases the risk of infection, and chronic diarrhea which in turn decrease drug absorption and impair metabolism.
CSI is an attempt in capturing the varying patterns of thought processes in a unitary scale that is psychometrically sound and overcomes the limitation of several other scales in terms of administration difficulty.
In case of administration difficulties, the content was to be put on a spoon and administered with a small amount of liquid.
Moreover, DIF analysis was used to examine the difference in the difficulty papameters between two modes of administration (paper-and-pencil vs. touch-screen).
Murtaza's objections to drone warfare include the difficulty of surrender, the Obama administration's looseness in defining potential targets and the common criticism that the relative cheapness of drone warfare encourages less public scrutiny.
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