Edwards immediately encountered significant challenges, including the difficulties of administering a college across two campuses, as well as old prejudices and hard feelings among those still loyal to either Jefferson College or Washington College.
Small numbers are apparent in this group due to the difficulties of administering a suite of questionnaires, including a 52-item fatigue measure, in a short clinic appointment.
I recognise, however, the difficulty of administering in a cost-effective way a benefits system of such complexity.
They share the common principle of administering an odorant prior to the execution of related mental operations with varying degrees of difficulty [ 7].
Kane presented a paper to the American Academy of Railway Surgeons in 1900 addressing the difficulty of administering intravenous infusions in the field.
Mr. Bloomberg's biggest problem with the program has been the difficulty of administering it.
The appellate court reversed, noting that "there are no principles of law which allow a court to rule out certain tortious [i.e. liability-causing] conduct by reason of general roughness of the game or the difficulty of administering it," and that "[t]he general customs of football do not approve the intentional punching or striking of others".
In a further study, Esposito et al. (2012) hypothesized that the logistical difficulty of administering two 0.25 ml doses in un-primed children may result in poor compliance and reduced immunogenicity, and as such, evaluated two 0.25 ml doses vs. one 0.5 ml dose of virosomal subunit influenza vaccine (Inflexal ® V, Crucell).
However, intriguingly, despite the increased morbidity and the difficulty of administering standard care, data on outcome, although conflicting, are showing predominantly either equal or lower mortality in obese than in normal weight critically ill patients, while only a few reported higher mortality [ 8, 9].
