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The difficulty of accurate and comprehensive identification of regulatory mutations has hindered evolutionary studies on their functional importance.
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Impostor feelings have a way of festering silently for a long time, thanks to the difficulty of accurate self-assessment and the social stigma of asking for help.
This technology was originally developed using polyacrylamide gel [ 16, 17] and had the main drawbacks of fragility and difficulty of accurate handling, although it has already enabled us to culture bacteria and perform PCR reactions [ 17].
Such an assessment may however be constrained by limited evidence of effectiveness of N-LEI in heart failure patients without prior hospitalisation, and by the difficulty (in the absence of accurate and timely information from population-based registries) of obtaining realistic estimates of annual risk of death and number of expected hospitalisations per patient.
Our survey concurs with the findings of others, that the difficulty of accurate data collection is compounded by duplication and unnecessary complexity caused by a multiplicity of registers [7].
This study is based on long-term memory of adiposity between childhood and young adulthood, which may generate important error measurements because many people cannot precisely evaluate their weight and height in childhood, either because of difficulty of accurate recall measurements or because they were not informed of their weight when young.
If we had included training blocks with a mix of accurate and inaccurate difficulty labels, participants may have learned even sooner that the difficulty labels did not appear to reflect actual task difficulty, and thus our results may not have been as strong.
One of the problems associated with this injury is the difficulty of its accurate and early recognition.
We had relied on overcoming to some extent the difficulty of accurate compass navigation caused by this frequent change of wind speed by the good landmarks near and along our track.
Regarding the difficulty of accurate interpretation of TCD's values, improvement of TCD's use is necessary.
This discrepancy may be due to the difficulty of accurate quantification of ssRNA viruses coupled with a preferential capture of smaller RNA products in the library preparation.
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