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This matrix can be viewed as a difficulty map situated over the 3D surface and is used to limit the propagation speed of the Fast Marching wave in order to find the best path depending on the task requirements, e.g., the least energy consumption path, the fastest path, or the most plain terrain.
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Researchers will apply fuzzy-trace theory, believing that jurors often understand the gist of damages but have difficulty mapping verbatim numbers (dollar awards) onto that gist.
Further, students tend to have difficulty mapping their intuitive understandings to formal representations and evaluating alternate representations (Sherin 2001).
Based on these criteria, it is apparent that the mapping studies had difficulty mapping our dataset compared to their original validation studies.
Interestingly, the previously undetermined breakpoint junctions in these two patients have one end within an LCR, leading to large uncertainty regions (~62-230 Kb) in the aCGH data, and difficulty mapping the junctions at sequence resolution for breakpoint junctions.
This was done to confirm that Bowtie has difficulties mapping reads that span two exons.
Patients can show difficulties mapping sensory perception into semantic knowledge, such as the disordered translation of auditory input into semantics in word deafness and Wernicke's aphasia (Goldblum and Albert, 1972; Tanaka et al., 1987; Poeppel, 2001; Slevc et al., 2011; Robson et al., 2013).
These five sorts of models correspond to three different psychological hypotheses: Linear approach (models 1 and 2) - The declared motivation is a faithful reflection of the motivational state of the individual, this motivational state is bounded and the subject has no difficulty to map it on the obliged interval.
Finally, and most importantly, it can be originated by the intrinsic difficulty to map patterns observed in a conceptual network, constructed on a specific perturbation strategy of a system, to the underlying structural organization and function of that very same system.
Interestingly, the presence of low complexity DNA inside the target region results in reduced sequence coverage because of the difficulty to map uniquely the short Illumina reads and will require additional efforts in order to produce sufficient sequence coverage required for accurate SNP identification.
CREST is prone to miss true-positive loci due to the difficulty to map split reads.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com