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Transfection difficulty manifests itself, especially in the cotransfection of mammalian cells.
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The difficulty manifested in gait as largely greater inconsistency in the pattern of strides than in the mean of the stride interval time series.
The difficulties manifest themselves in several ways.
The difficulties manifest themselves, one after the other, as their effects ripple through the system.
Academic and/or underlying cognitive difficulties manifesting as listening difficulties may contribute to a child being referred for clinical assessment.
Emotional difficulties, manifested in feelings of isolation and withdrawal from social interaction, were reported by participants in all four groups.
The difficulties manifested at several levels: negotiating safe sex prior to disclosure; knowing at what point to disclose; knowing how to do it.
In fact, apart from a few studies such as Lewis and Freebairn (1992, 1998) and Tomblin et al. (1992), there have been relatively few studies investigating how language difficulties manifest themselves in the adult population.
The difficulty is manifested in the fact that as soon as we try to pin down the minimal, threshold conditions of autonomous agency, we seem to come up against the conditions necessary for agency itself.
First, the integration effect would have difficulty to manifest itself without the integrator.
Here are some ways this difficulty might manifest itself: The person might not recognize when they've said something hurtful, or when they're making someone uncomfortable in a conversation.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com