Sentence examples for difficulty in the development from inspiring English sources

These shortages cause much difficulty in the development of the silicon-based materials as commercial anode materials.

Literature confirms the difficulty in the development of objective measures for flexibility, for example, because of its property of multidimensionality.

The main difficulty in the development of ATP antagonist kinase inhibitors is target specificity, since the ATP-binding motif is present in many proteins.

For samples of CaCu2.9Ti4O12, the lower dielectric constant can be attributed to the smaller grain boundary areas and the difficulty in the development of domains inside the fine grains.

An additional difficulty in the development of QSAR models is the fact that some regression methods have parameters that need to be optimised to obtain the best performance for a particular problem.

The difficulty in the development of anticancer medicines is well reflected in the fact that only 5% of the candidates entering clinical trials reach the approval for marketing [1].

It may also explain difficulties in the development of vaccines and tools for immunodiagnosis.

Such an approach suffers from the following drawbacks: (1) Difficulties in the development and maintenance of application programs.

The multiple sequence and antigenic variability of HIV-1 has led to unprecedented difficulties in the development of effective vaccines.

Due to lack of the detailed data of precipitation resources in the region, there have been some difficulties in the development of rainwater harvesting agriculture.

It is associated with a number of additional impairments including delays and difficulties in the development of language, verbal short-term memory, and speech production.