However, as residual fat-signal (hyperintense at T1-weighted images) may cause difficulties in interpretation, the calculation of subtraction images from the pre- and post-contrast series is recommended [ 22, 23].
The low proportion of pathologically confirmed BSE cases in the positive control group presents further difficulty in interpretation of the findings since it suggests that if the probability of detection of prion disease in the test groups was similar or less, a negative result was the more likely outcome.
However, 2D graphics contain several symbols that only professionals would understand, thus leading to difficulty in interpretation of the information for managers (Tsai et al. 2014a).
However, this feature of calprotectin gives rise to more difficulty in interpretation of the results in this age group, with more false positive test results.
For instance, concerning the clonogenic ability: several studies reported that the SP cells possess higher clonogenicity than the MP cells [ 35– 38], whereas others including our previous study found no such a difference between them [ 32, 33, 41], indicating certain difficulty in interpretation of the SP phenotype.
Children under 15 months were not recruited because of the difficulty in interpretation of results with the antibody-based spot tests that were used.
27, 88– 94 The main difficulty in interpretation is due to the interplay of different pathways and also to the existence of functional redundancies between signalling molecules or/and between their membrane receptors.
The magnitude of these effects may be of high importance clinically but the difficulty in interpretation, particularly with regard to the existence of hospitals with identical underlying mortality risk, may limit their usefulness.
Residual dialysate fluid when present has the potential to obscure some of the inflammatory changes in the mesentery or create difficulty in interpretation, as it may be the cause of thickening of the intestinal or gallbladder wall.
This highlights the difficulty in interpretation of our findings (and those of other similar studies) because the causal pathways are unclear.
