Sentence examples for difficulty in development from inspiring English sources

Major difficulty in development of dengue diagnostics is availability of suitable antigens.

Currently, the northern block of the Xingshugang Oilfield is in the late stage of development and is facing problems due to the scattered distribution of remaining oil and difficulty in development adjustments.

However, the difficulty in development of effective drugs may be the challenge in designing specific inhibitors for a single DUB.

SITP lines and the ordinary bus routes may facilitate the access to the TransMilenio, increasing the number of its potential users, even if difficulties in development and implementation of the integrated system have been experienced (Hidalgo and King 2014; Kash and Hidalgo 2014; Urazán Bonells and Velandia Durán 2012).

This could result in difficulties in development of an antioxidant supplementation.

However, more systematic analyses of the direct effects of HMW-GS genes on grain properties are difficult due to technical difficulties in development of an ideal transgenic line that has the target HMW-GS gene over-expressed without affecting other endogenous genes' expression in wheat grains.

It is this complexity which explains the difficulty in the development of effective strategies for prevention of cognitive impairment in people with diabetes and in the development of treatment approaches in those patients who have already become cognitively impaired.

Such effects are often associated with a difficulty in the development of resistance to antimicrobials31.

Literature confirms the difficulty in the development of objective measures for flexibility, for example, because of its property of multidimensionality.

The main difficulty in the development of ATP antagonist kinase inhibitors is target specificity, since the ATP-binding motif is present in many proteins.

For samples of CaCu2.9Ti4O12, the lower dielectric constant can be attributed to the smaller grain boundary areas and the difficulty in the development of domains inside the fine grains.